Main Areas of Research

 

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Function of the extracellular matrix in the embryonic and adult central nervous system.   

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Molecular basis of synapse formation at the neuromuscular junction and in the developing central nervous system.
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The role of agrin and of its receptor complex (MuSK and Lrp4) in the brain and in skeletal muscle tissue. 
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Structure and function of muscle spindles in wildtype and transgenic mice, particularly in murine model systems for neuromuscular diseases.

 

 

 

 
Collaborations
  
  international
  Dr. Markus Ruegg Biocenter University of Basel Switzerland
  Dr. Hélène Puccio Faculté de Médecine et de Pharmacie Lyon France
  Dr. Reginald Bittner Center for Anatomy and Cell Biology, University of Vienna Austria
         
 
  national
  Dr. Heinrich Brinkmeier Institute for Pathophysiology Greifswald
  Dr. Fritz G. Rathjen Max Delbrueck Center for Molecular Medicine Berlin
  Dr. Carmen Birchmeier Max Delbrueck Center für Molecular Medicine Berlin
  Dr. Benedikt Schoser Friedrich Baur Center of the Neurology Department Ludwig Maximilians University