Several projects are currently investigated in my lab: We analyze the function of agrin in the developing and the adult central nervous system and we investigate the structure and function of muscle spindles in wildtype and genetically altered mice.

What are the molecular mechanisms which regulate the formation of synapses in the developing CNS, and do these mechanisms also play a role in the adult brain, for example during plastic changes of synapses in processes like learning and memory?
Does the extracellular matrix molecule agrin play a role in the CNS which is similar to its role at the neuromuscular junction? Is agrin also a key-regulator of synapse formation alsoin the developing and adult CNS?
What role does the agrin receptor complex play during CNS development as well as in the adult brain?
How du muscle spindles function and how are they altered in transgenic mice, in particular in models of neuromuscular disorders?