ausgewählte Veröffentlichungen |
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2023 | Watkins, B., Schultheiß, J., Rafuna, A., Hintze, S., Meinke, P., Schoser, B.. und Kröger, S. (2023) Degeneration of muscle spindles in a murine model of Pompe disease. Scientific Reports 13: 6555; DOI: 10.1038/s41598-023-33543-y | ||
Bornstein, B., Watkins, B., Passini, F.S., Blecher, R., Assaraf, E., Sui, X.M., Brumfeld, V., Tsoory, M., Kröger, S. und Zelzer, E. (2023). The mechanosensitive ion channel ASIC2 mediates both proprioceptive sensing and spinal alignment. Experimental Physiology DOI: 10.1113/EP090776 |
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2022 | Watkins, B., Schuster, H.M., Gerwin, L., Schoser, B. und Kröger, S. (2022) The effect of methocarbamol and mexiletine on murine muscle spindle function. Muscle Nerve 66: 96-105. | ||
Jacquier, A., Risson, V., Simonet, T., Roussange, F., Lacoste, N., Ribault, S., Carras, J., Theuriet, J., Girard, E., Grosjean, I., Le Goff, L., Kröger, S., Meltoranta, J., Bauche, S., Sternberg, D., Fournier, E., Kostera-Pruszczyk, A., O'Connor, E., Eymard, B., Lochmüller, H., Martinat, C. and Schaeffer, L. (2022) Severe congenital myasthenic syndromes caused by agrin mutations affecting secretion by motoneurons. Acta Neuropathologica 144: 707-731. |
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2021 | Doppler, K., Hemprich, A., Haarmann, A., Brecht, I., Franke, M., Kröger, S., Villmann, C. und Sommer, C. (2021) Autoantibodies to cortactin and agrin in sera of patients with myasthenia gravis. Journal of Neuroimmunology 356: 577588. |
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Kröger S. und Watkins B. (2021) Muscle spindle function in healthy and diseased muscle.Skeletal Muscle 11: 3. |
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Zhang Y., Otto P., Qin L., Eiber N., Hashemolhosseini S., Kröger S., Brinkmeier H. (2021) Methocarbamol blocks muscular Nav 1.4 channels and decreases isometric force of mouse muscles. Muscle & Nerve 63: 141-150. | |||
2020 |
Gerwin, L.,
Rossmanith, S., Haupt, C., Schultheiß, J., Brinkmeier,
H., Bittner, R.E., Kröger,
S. (2020) Impaired
muscle spindle
function in murine models of muscular dystrophy. The
Journal of Physiology 598:1591-1609. |
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2019 |
Gerwin, L., Haupt, C., Wilkinson, K.A., and
Kröger, S. (2019).
Acetylcholine receptors in the equatorial region of
intrafusal muscle fibres
modulate mouse muscle spindle sensitivity. The
Journal of Physiology 597: 1993-2006. |
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Handara,
G., and Kröger, S.
(2019). Alternative splicing and the intracellular
domain mediate TM-agrin's ability to differentially
regulate the density of excitatory and inhibitory
synapse-like specializations in developing CNS neurons. Neuroscience
419:
60-71.
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Handara, G., Hetsch, F. J. A., Jüttner, R., Schick, A., Haupt, C., Rathjen, F. G., and Kröger, S. (2019) The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons. Developmenal Biology 445: 54-67. | |||
2018 | Kröger, S. (2018) Proprioception 2.0: novel functions for muscle spindles. Current Opinion in Neurology 31: 592-598. | ||
2017 | Karakatsani, A., Marichal, N., Urban, S., Kalamakis, G., Ghanem, A., Schick, A., Zhang, Y., Conzelmann, K. K., Ruegg, M. A., Berninger, B., Ruiz de Almodovar, C., Gascon, S., and Kröger, S. (2017) Neuronal LRP4 regulates synapse formation in the developing CNS. Development 144: 4604-4615. | ||
Schmidt, N., Basu, S., Kröger, S., and Brenner, H. R. (2017) A Cell Culture System to Investigate the Presynaptic Control of Subsynaptic Membrane Differentiation at the Neuromuscular Junction. Methods in Molecular Biology 1538, 3-11. | |||
2016 | Schneider, S., Gruart, A., Grade, S., Zhang, Y., Kröger, S., Kirchhoff, F., Eichele, G., Delgado Garcia, J. M., and Dimou, L. (2016) Decrease in newly generated oligodendrocytes leads to motor dysfunctions and changed myelin structures that can be rescued by transplanted cells. Glia 64: 2201-2218. | ||
2015 | Zhang Y., Lin S., Karakatsani A., Rüegg M., Kröger S. (2015) Differential regulation of AChR clustering in the polar and equatorial region of murine muscle spindles. European Journal of Neuroscience 41: 69-78. | ||
2014 | Gasperi C., Melms A., Schoser B., Zhang Y., Meltoranta J., Risson V., Schaeffer L., Schalke B., Kröger S. (2014) Anti-Agrin Autoantibodies in Myasthenia gravis. Neurology 82: 1976-1983. | ||
Zhang Y., Wesolowska M., Karakatsani A., Wizemann V., Kröger S. (2014) Formation of cholinergic synapse-like specializations at developing murine muscle spindles. Developmental Biology 393: 227-235. | |||
Steiner E., Enzmann G.U., Lyck R., Lin S., Rüegg M.A., Kröger S., Engelhardt B. (2014) The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions. Cell and Tissue Research 358: 465-479. | |||
2013 | Choi, H.Y., Liu, Y., Tennert, C., Sugiura, Y., Karakatsani, A., Kröger, S., Johnson, E.B., Hammer, R.E., Lin, W., Herz, J., (2013) APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice. Elife 20: 2:e00220. doi: 10.755/eLife.00220. | ||
2012 | Pevzner, A., Schoser, B.,Peters, K., Cosma, N.C., Karakatsani, A., Schalke, B., Melms, A., and Kröger, S. (2012). Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis. Journal of Neurology 259: 427-435. | ||
Burk, K., Desoeuvre, A., Boutin, C., Smith, M.A., Kröger, S., Bosio, A., Tiveron, M.C., and Cremer, H. (2012). Agrin-signaling is necessary for the integration of newly generated neurons in the adult olfactory bulb. Journal of Neuroscience 32: 3759-3764. | |||
2010 | Patzke C., Max K.E.A., Behlke J., Schreiber J., Schmidt H., Dorner A., Kröger S., Henning M., Otto A., Heinemann U., und Rathjen F.G. (2010) The coxsackievirus-adenovirus receptor reveals complex homophilic and heterophilic interactions on neural cells. Journal of Neuroscience 30: 2897-2910. | ||
Porten E., Seliger B., Schneider V.A., Wöll S., Stangel D., Ramseger R., und Kröger S. (2010) The process-inducing activity of transmembrane agrin requires follistatin-like domains. The Journal of Biological Chemistry 285: 3114-3125. |
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2009 | Kröger,S. und Pfister,H.
(2009) Agrin in the nervous system - synaptogenesis and
beyond. Future Neurology 4:
67-86 |
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Ramseger,R., White,R., und
Kröger,S. (2009) Transmembrane form agrin-induced process
formation requires lipid rafts and the activation of Fyn
and MAPK. The Journal of Biological Chemistry 284:
7697-7705. |
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Jimenez-Mallebrera C., Torelli S., Feng L., Kim J., Godfrey C., Clement E., Mein R., Abbs S., Brown S.C., Campbell K.P., Kröger S., Talim B., Topaloglu H., Quinlivan R., Roper H., Childs A.M., Kinali M., Sewry C.A., und Muntoni F. (2009) A comparative study of alpha-dystroglycan glycosylation in dystroglycanopathies suggests that the hypoglycosylation of alpha-dystroglycan does not consistently correlate with clinical severity. Brain Pathology 19: 596-611. | |||
2008 | Yamamoto,T.; Kato,Y.;
Kawaguchi-Niida,M.; Shibata,N.; Osawa,M.; Saito,K.;
Kröger,S.; und Kobayashi,M. (2008) Characteristics of
neurons and glia in the brain of Fukuyama type congenital
muscular dystrophy. Acta Myologica 27:
9-13 |
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2007 | Schröder, J.E.; Tegeler,
M.; Großhans, U.; Porten, E.; Blank, M.; Lee, J.; Esapa,
C.; Blake, D.J., und Kröger, S. (2007) Dystroglycan
regulates structure, proliferation and differentiation of
neuroepithelial cells in the developing vertebrate CNS. Developmental
Biology 307: 62-78 |
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Noell, S., Fallier-Becker,
P., Becker, C., Kröger, S., Mack, A.F., und Wolburg, H.
(2007) Effects of agrin on the expression and distribution
of the water channel protein aquaporin-4 and volume
regulation in cultured astrocytes. European Journal
of Neuroscience 26: 2109-2118 |
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2006 | Annies, M., Bittcher, G., Ramseger, R., Löschinger, J., Wöll, S., Porten, E., Abraham, C., Rüegg, M.A., und Kröger, S. (2006) Clustering of transmembrane-agrin induces filopodia-like processes on axons and dendrites. Molecular and Cellular Neuroscience 31: 515-524. | ||
Jastrow. H., Koulen, P., Altrock, W.D., und Kröger, S. (2006) Identification of a b-dystroglycan immunoreactive sub-compartment in photoreceptor terminals. Investigative Ophthalmology and Visual Science 47: 17-24. |
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2005 | Saito, F., Blank, M., Schröder, J., M anya, H., Shimizu, T., Campbell, K.P., Endo, T., Mizutani, M., Kröger, S. , und Matsumura, M. (2005) Aberrant glycosylation of a -dystroglycan causes defective binding of laminin in the muscle of chicken muscular dystrophy. FEBS Letters 579: 2359-2363 . | ||
Schnepp A., Lindgren P., Hülsmann H., Kröger S, Paulsson M., und Hartmann U. (2005) Mouse testican-2: Expression, glycosylation and effects on neurite outgrowth. Journal of Biological Chemistry 280: 11274-11280. |
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2004 | Saito, F., Blank, M.,
Schröder, J., Manya, H., Shimizu, T., Campbell, K.P.,
Endo, T., Mizutani, M., Kröger, S., und Matsumura, K.
(2004) Aberrant glycosylation and defective
laminin-binding of alpha-dystroglycan in chicken muscular
dystrophy. Neuromuscular Disorders 14:
603-604. |
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Brown, S.C., Torelli, S., Brockington, M., Yuva, Y., Jimenez, C., Feng, L., Anderson, L., Ugo, I., Kröger, S., Bushby, K., Voit, T., Sewry, C., und Muntoni, F. (2004) Abnormalities in a-Dystroglycan Expression in MDC1C and LGMD2I Muscular Dystrophies. American Journal of Pathology 164: 727-737. | |||
Warth A., Kröger, S., und Wolburg, H. (2004) Loss of agrin immunoreactivity from brain capillary basal laminae correlates with the redistribution of aquaporin-4 in human glioblastoma multiforme. Acta Neuropathologica 207: 311-318. | |||
Herzog, C., Has, C., Franzke, C.-W., Echtermeyer, F.G., Kröger, S., Gustafsson, E., Fässler, und R., Bruckner-Tuderman, L. (2004) Dystroglycan in skin and cutaneous cells: b-subunit is shed from the cell surface. Journal of Investigative Dermatology 122: 1372-1380. | |||
2003 | Esapa, C.T., Bentham, G.R.B., Schröder, J.E., Kröger, S., und Blake, D.J. (2003) The effects of post-translational processing on dystroglycan synthesis and trafficking. FEBS Letters, 555: 209-216. | ||
2002 | Annies, M.,
und Kröger, S. (2002) Isoform pattern and AChR aggregation
activity of agrin expressed by embryonic chick retinal
ganglion neurons. Molecular and Cellular Neuroscience
20: 525-535. |
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Esapa, C. T.,
Benson M. A., Schröder, J. E., Martin-Rendon, E.,
Brockington, M., Brown, S.C., Muntoni, F., Kröger, S., und
Blake, D.J. (2002) Functional requirements for
fukutin-related protein in the Golgi apparatus. Human
Molecular Genetics 11: 3319-3331. |
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Kröger, S., und Schröder,
J. E. (2002) Agrin in the CNS: New roles for a synapse
organizer. News in Physiological Science 17:
207-212. |
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Rascher, G., Fischmann,
A., Kröger, S., Duffner, F., Grote, E. H., und Wolburg, H.
(2002) Extracellular matrix and the blood-brain barrier in
glioblastoma multiforme: spatial segregation of tenascin
and agrin. Acta Neuropathologica, 104:
85-91. |
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Blank, M., Blake, D.J. und Kröger, S. (2002) Molecular heterogeneity of dystrophin-like complexes in the developing and adult retina. Neuroscience, 111: 259-273. |
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Kröger, S. (2002) Agrin: ein Hauptregulator der Synapsenbildung. BIOforum 12: 49-51 | |||
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2001 | Kröger, S. (2001)
Extracellular signals regulating nervous system
development. In: The Neurosciences at the Turn of the
Century. Seite 669-672; Ed. N. Elsner und G. W.
Kreutzberg; Thieme Verlag Stuttgart |
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Neumann F.R., Bittcher,
G., Annies, M. Schumacher, B. Kröger, S., und Ruegg, M.A.
(2001) An alternative amino-terminus expressed in the
central nervous system converts agrin to a type II
transmembrane protein. Molecular and Cellular
Neuroscience 17: 208-225. |
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Yard, B. A.,
Kahlert, S., Engelleiter, R., Resch, S., Waldherr, R.,
Groffen, A. J., van den Heuvel, L. P. W. J., van der Born,
J., Berden, J. H. M., Kröger, S., Hafner, M., und van der
Woude, F. J. (2001). Decreased glomerular expression of
agrin in diabetic nephropathy and podocytes, cultured in
high glucose medium. Experimental Nephrology 9:
214-222. |
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Schröder,
J.E., Tegeler, M., und Kröger, S. (2001) Die molekulare
Grundlage von Muskeldystrophien. BioForum 11:
2-4. |
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2000 | Hering, H., Koulen, P.,
und Kröger, S. (2000) Distribution and subcellular
concentration of b1 integrin
in radial cells of the developing and adult avian retina.
Journal of Comparative Neurology 424:
153-164. |
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Blake, D.J.,
und Kröger, S. (2000) The neurobiology of Duchenne
Muscular Dystrophy: learning lessons from muscle? Trends
in Neurosciences 23: 92-99. |
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Herrmann, R., Straub V.,
Blank, M., Kutzick, C., Franke, N., Neuen Jacob, E.,
Lenard, H.-G., Kröger, S., und Voit, T. (2000)
Dissociation of the dystroglycan-complex in
caveolin-3-deficient Limb Girdle Muscular Dystrophy. Human
Molecular Genetics 9: 2335-2340. |
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1999 | Hering, H. und Kröger, S.
(1999) Synapse formation and agrin expression in
stratospheroid cultures from embryonic chick retina. Developmental
Biology 214: 412-428. |
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Koulen, P., Honig, L.S.,
Fletcher, E.L. und Kröger, S. (1999) Expression,
distribution, and ultrastructural localization of the
synapse-organizing molecule agrin in the mature avian
retina. European Journal of Neuroscience 11:
4188-4196. |
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Blank, M., Koulen, P.,
Blake, D., und Kröger, S. (1999) Dystrophin and
beta-dystroglycan in photoreceptor terminals from normal
and mdx3Cv mouse retinae. European
Journal of Neuroscience 11: 2121-2133. |
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1998 | Koulen, P., Blank, M., und
Kröger, S. (1998) Differential distribution of
b-dystroglycan in rabbit and rat retina. Journal of
Neuroscience Research 51: 735-747. |
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1997 | Kröger, S. (1997)
Differential distribution of agrin isoforms in the
developing and adult avian retina. Molecular and
Cellular Neuroscience 10: 149-161. |
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Blank, M.,
Koulen, P., und Kröger, S. (1997) Subcellular
concentration of b-dystroglycan
in photoreceptor terminals and Müller glial cells of the
chick retina. Journal of Comparative Neurology 389:
668-678. |
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Galarraga, E., und Kröger,
S. (1997) Connections between neuroscientists from Europe
and Latin America reinforced. Trends in Neurosciences
20: 549-551. |
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Sorokin, L.
M., Pausch, F., Frieser, M., Kröger, S., Ohage, E., und
Deutzmann, R. (1997) Developmental regulation of the
laminin a5 chain suggests a
role in epithelial and endothelial cell maturation. Developmental
Biology 189: 285-300. |
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Kröger, S. (1997)
Molecular determinants involved in nervous system
development. In: From Membrane to Mind. Seite
430-433; N. Elsner und H. Wässle; Thieme Verlag,
Stuttgart. |
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Reiss, Y., Layer, P. G.,
und Kröger, S. (1997) Butyrylcholinesterase-positive cells
of the developing chicken retina that are noncholinergic
and GABA positive. Developmental Brain Research 100:
62-72. |
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Koulen, P., Brandtstätter,
J. H., Kröger, S., Enz, R., Bormann, J., und Wässle, H.
(1997) Immunocytochemical localization of the GABAC
receptor r-subunits in the
cat, goldfish and chicken retina. Journal of
Comparative Neurology 380: 520-532. |
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1996 | Mann, S., und Kröger, S.
(1996) Agrin is synthesized by retinal cells and
colocalizes with gephyrin. Molecular and Cellular
Neuroscience 8: 1-13. |
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Hering, H.,
und Kröger, S. (1996) Formation of synaptic
specializations in the inner plexiform layer of the
developing chick retina. Journal of Comparative
Neurology 375: 393-405. |
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Reiss, Y., Kröger, S.,
Grassi, J., Tsim, K.W.K., Willbold, E., und Layer, P.G.
(1996) Extracellular and asymmetric forms of
acetylcholinesterase are expressed on cholinergic and
non-cholinergic terminal neuropil of the developing chick
retina. Cell and Tissue Research 286:
13-22. |
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Jones, G., Herczeg, A.,
Ruegg, M.A., Lichtsteiner, M., Kröger, S., und Brenner,
H.R. (1996) Substrate-bound agrin induces expression of
acetylcholine receptor e-subunit gene in cultured
mammalian muscle cells. Proceedings of the National
Academy of Science (USA) 93: 5985-5990. |
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Kröger, S., und Mann, S.
(1996) Biochemical and functional characterization of
basal lamina-bound agrin in the central nervous system. European
Journal of Neuroscience 8: 500-509. |
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Kirsch, J.,
und Kröger, S. (1996) Postsynaptic anchoring of receptors:
A cellular approach to neuronal and muscular sensitivity.
The Neuroscientist 2: 100-108. |
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Kröger, S.,
Horton, S.E., und Honig, L.S. (1996) The developing avian
retina expresses agrin isoforms during development. Journal
of Neurobiology 29: 165-182. |
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1995 | Tsen, G. Halfter, W. Kröger, S., und Cole, G.J. (1995) Agrin is a heparan sulfate proteoglycan. Journal of Biological Chemistry 270: 3392-3399. | ||
1992 | McMahan, U.J., Horton,
S.E., Werle, M.J., Honig, L.S., Kröger, S., Ruegg, M.A.,
und Escher, G. (1992) Agrin isoforms and their role in
synaptogenesis. Current Oppinion in Cell Biology 4:
869-874. |
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Ruegg, M.A., Tsim, K.W.K.,
Horton, S.E., Kröger, S., und McMahan, U.J. (1992) The
agrin gene codes for a family of basal lamina proteins
that differ in function and distribution. Neuron 8:
691-699. |
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Tsim, K.W.K.,
Ruegg, M.A., Escher, G., Kröger, S., und McMahan, U.J.
(1992). cDNA that encodes active agrin. Neuron 8:
677-689. |
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1991 | Kröger, S.,
und Walter, J. (1991). Molecular mechanisms separating two
axonal pathways during development of the avian optic
tectum. Neuron 6: 291-303. |
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1990 | Kröger, S., und Schwarz,
U. (1990). The avian tectobulbar tract: Development,
explant culture, and effects of antibodies on the pattern
of neurite outgrowth. Journal of Neuroscience 10:
3118-3134. |
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Kröger, S., und
Niehörster, L. (1990). Isolation, characterization and
substrate properties of the external limiting membrane
from the avian embryonic optic tectum. Journal of
Neuroscience Research 27: 169-183. |
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1987 | Halfter, W., Reckhaus, W.,
und Kröger, S. (1987). Nondirected axonal growth on basal
lamina from avian embryonic retina. Journal of
Neuroscience 7: 3712-3722. |