Watkins, B., Schultheiß, J., Rafuna, A., Hintze, S., Meinke, P., Schoser, B.. und Kröger, S. (2023) Degeneration of muscle spindles in a murine model of Pompe disease. Scientific Reports13: 6555; DOI: 10.1038/s41598-023-33543-y
Bornstein, B., Watkins, B., Passini, F.S., Blecher, R., Assaraf, E., Sui, X.M., Brumfeld, V., Tsoory, M., Kröger, S. und Zelzer, E. (2023). The mechanosensitive ion channel ASIC2 mediates both proprioceptive sensing and spinal alignment. Experimental Physiology DOI: 10.1113/EP090776
2022
Watkins, B., Schuster, H.M., Gerwin, L., Schoser, B. und Kröger, S. (2022) The effect of methocarbamol and mexiletine on murine muscle spindle function. Muscle Nerve66: 96-105.
Jacquier, A., Risson, V., Simonet, T., Roussange, F., Lacoste, N., Ribault, S., Carras, J., Theuriet, J., Girard, E., Grosjean, I., Le Goff, L., Kröger, S., Meltoranta, J., Bauche, S., Sternberg, D., Fournier, E., Kostera-Pruszczyk, A., O'Connor, E., Eymard, B., Lochmüller, H., Martinat, C. and Schaeffer, L. (2022) Severe congenital myasthenic syndromes caused by agrin mutations affecting secretion by motoneurons. Acta Neuropathologica144: 707-731.
2021
Doppler, K., Hemprich, A., Haarmann, A., Brecht, I., Franke, M., Kröger, S., Villmann, C. und Sommer, C. (2021) Autoantibodies to cortactin and agrin in sera of patients with myasthenia gravis. Journal of Neuroimmunology356: 577588.
Kröger S. und Watkins B. (2021) Muscle spindle function in healthy and diseased muscle.Skeletal Muscle11: 3.
Zhang Y., Otto P., Qin L., Eiber N., Hashemolhosseini S., Kröger S., Brinkmeier H. (2021) Methocarbamol blocks muscular Nav 1.4 channels and decreases isometric force of mouse muscles.
Muscle & Nerve63: 141-150.
2020
Gerwin, L.,
Rossmanith, S., Haupt, C., Schultheiß, J., Brinkmeier,
H., Bittner, R.E., Kröger,
S. (2020) Impaired
muscle spindle
function in murine models of muscular dystrophy. The
Journal of Physiology 598:1591-1609.
2019
Gerwin, L., Haupt, C., Wilkinson, K.A., and
Kröger, S. (2019).
Acetylcholine receptors in the equatorial region of
intrafusal muscle fibres
modulate mouse muscle spindle sensitivity. The
Journal of Physiology597: 1993-2006.
Handara,
G., and Kröger, S.
(2019). Alternative splicing and the intracellular
domain mediate TM-agrin's ability to differentially
regulate the density of excitatory and inhibitory
synapse-like specializations in developing CNS neurons. Neuroscience419:
60-71.
Handara, G., Hetsch, F. J.
A., Jüttner, R., Schick, A., Haupt, C., Rathjen, F. G.,
and Kröger, S. (2019) The role of agrin, Lrp4 and MuSK
during dendritic arborization and synaptogenesis in
cultured embryonic CNS neurons. Developmenal Biology445: 54-67.
2018
Kröger, S. (2018)
Proprioception 2.0: novel functions for muscle spindles. Current
Opinion in Neurology31: 592-598.
2017
Karakatsani, A., Marichal,
N., Urban, S., Kalamakis, G., Ghanem, A., Schick, A.,
Zhang, Y., Conzelmann, K. K., Ruegg, M. A., Berninger, B.,
Ruiz de Almodovar, C., Gascon, S., and Kröger, S. (2017)
Neuronal LRP4 regulates synapse formation in the
developing CNS. Development144:
4604-4615.
Schmidt, N., Basu, S.,
Kröger, S., and Brenner, H. R. (2017) A Cell Culture
System to Investigate the Presynaptic Control of
Subsynaptic Membrane Differentiation at the Neuromuscular
Junction. Methods in Molecular Biology 1538, 3-11.
2016
Schneider, S., Gruart, A.,
Grade, S., Zhang, Y., Kröger, S., Kirchhoff, F., Eichele,
G., Delgado Garcia, J. M., and Dimou, L. (2016) Decrease
in newly generated oligodendrocytes leads to motor
dysfunctions and changed myelin structures that can be
rescued by transplanted cells. Glia64:
2201-2218.
2015
Zhang Y., Lin S.,
Karakatsani A., Rüegg M., Kröger S. (2015) Differential
regulation of AChR clustering in the polar and equatorial
region of murine muscle spindles. European Journal of
Neuroscience41: 69-78.
2014
Gasperi C., Melms A.,
Schoser B., Zhang Y., Meltoranta J., Risson V., Schaeffer
L., Schalke B., Kröger S. (2014) Anti-Agrin Autoantibodies
in Myasthenia gravis. Neurology82:
1976-1983.
Zhang Y., Wesolowska M.,
Karakatsani A., Wizemann V., Kröger S. (2014) Formation of
cholinergic synapse-like specializations at developing
murine muscle spindles. Developmental Biology393:
227-235.
Steiner E., Enzmann G.U.,
Lyck R., Lin S., Rüegg M.A., Kröger S., Engelhardt B.
(2014) The heparan sulfate proteoglycan agrin contributes
to barrier properties of mouse brain endothelial cells by
stabilizing adherens junctions. Cell and Tissue
Research358: 465-479.
2013
Choi, H.Y., Liu, Y.,
Tennert, C., Sugiura, Y., Karakatsani, A., Kröger, S.,
Johnson, E.B., Hammer, R.E., Lin, W., Herz, J., (2013) APP
interacts with LRP4 and agrin to coordinate the
development of the neuromuscular junction in mice. Elife20: 2:e00220. doi: 10.755/eLife.00220.
2012
Pevzner, A., Schoser,
B.,Peters, K., Cosma, N.C., Karakatsani, A., Schalke, B.,
Melms, A., and Kröger, S. (2012). Anti-LRP4 autoantibodies
in AChR- and MuSK-antibody-negative myasthenia gravis. Journal
of Neurology259: 427-435.
Burk, K., Desoeuvre, A.,
Boutin, C., Smith, M.A., Kröger, S., Bosio, A., Tiveron,
M.C., and Cremer, H. (2012). Agrin-signaling is necessary
for the integration of newly generated neurons in the
adult olfactory bulb. Journal of Neuroscience32:
3759-3764.
2010
Patzke C., Max K.E.A.,
Behlke J., Schreiber J., Schmidt H., Dorner A., Kröger S.,
Henning M., Otto A., Heinemann U., und Rathjen F.G. (2010)
The coxsackievirus-adenovirus receptor reveals complex
homophilic and heterophilic interactions on neural cells.
Journal of Neuroscience 30: 2897-2910.
Porten E., Seliger B., Schneider V.A., Wöll S.,
Stangel D., Ramseger R., und Kröger S. (2010) The
process-inducing activity of transmembrane agrin
requires follistatin-like domains. The Journal of
Biological Chemistry285:
3114-3125.
2009
Kröger,S. und Pfister,H.
(2009) Agrin in the nervous system - synaptogenesis and
beyond. Future Neurology4:
67-86
Ramseger,R., White,R., und
Kröger,S. (2009) Transmembrane form agrin-induced process
formation requires lipid rafts and the activation of Fyn
and MAPK. The Journal of Biological Chemistry284:
7697-7705.
Jimenez-Mallebrera C.,
Torelli S., Feng L., Kim J., Godfrey C., Clement E., Mein
R., Abbs S., Brown S.C., Campbell K.P., Kröger S., Talim
B., Topaloglu H., Quinlivan R., Roper H., Childs A.M.,
Kinali M., Sewry C.A., und Muntoni F. (2009) A comparative
study of alpha-dystroglycan glycosylation in
dystroglycanopathies suggests that the hypoglycosylation
of alpha-dystroglycan does not consistently correlate with
clinical severity. Brain Pathology19:
596-611.
2008
Yamamoto,T.; Kato,Y.;
Kawaguchi-Niida,M.; Shibata,N.; Osawa,M.; Saito,K.;
Kröger,S.; und Kobayashi,M. (2008) Characteristics of
neurons and glia in the brain of Fukuyama type congenital
muscular dystrophy. Acta Myologica 27:
9-13
2007
Schröder, J.E.; Tegeler,
M.; Großhans, U.; Porten, E.; Blank, M.; Lee, J.; Esapa,
C.; Blake, D.J., und Kröger, S. (2007) Dystroglycan
regulates structure, proliferation and differentiation of
neuroepithelial cells in the developing vertebrate CNS. Developmental
Biology307: 62-78
Noell, S., Fallier-Becker,
P., Becker, C., Kröger, S., Mack, A.F., und Wolburg, H.
(2007) Effects of agrin on the expression and distribution
of the water channel protein aquaporin-4 and volume
regulation in cultured astrocytes. European Journal
of Neuroscience26: 2109-2118
2006
Annies, M., Bittcher, G.,
Ramseger, R., Löschinger, J., Wöll, S., Porten, E.,
Abraham, C., Rüegg, M.A., und Kröger, S. (2006) Clustering
of transmembrane-agrin induces filopodia-like processes on
axons and dendrites. Molecular and Cellular
Neuroscience 31: 515-524.
Jastrow.
H., Koulen, P., Altrock, W.D., und Kröger, S. (2006)
Identification of a b-dystroglycan immunoreactive
sub-compartment in photoreceptor terminals. Investigative
Ophthalmology and Visual Science 47: 17-24.
2005
Saito, F., Blank, M.,
Schröder, J., M anya, H., Shimizu, T., Campbell, K.P.,
Endo, T., Mizutani, M., Kröger, S. , und Matsumura, M.
(2005) Aberrant glycosylation of a -dystroglycan causes
defective binding of laminin in the muscle of chicken
muscular dystrophy. FEBS Letters 579:
2359-2363 .
Schnepp
A., Lindgren P., Hülsmann H., Kröger S, Paulsson M., und
Hartmann U. (2005) Mouse testican-2: Expression,
glycosylation and effects on neurite outgrowth. Journal
of Biological Chemistry 280:
11274-11280.
2004
Saito, F., Blank, M.,
Schröder, J., Manya, H., Shimizu, T., Campbell, K.P.,
Endo, T., Mizutani, M., Kröger, S., und Matsumura, K.
(2004) Aberrant glycosylation and defective
laminin-binding of alpha-dystroglycan in chicken muscular
dystrophy. Neuromuscular Disorders 14:
603-604.
Brown, S.C., Torelli, S.,
Brockington, M., Yuva, Y., Jimenez, C., Feng, L.,
Anderson, L., Ugo, I., Kröger, S., Bushby, K., Voit, T.,
Sewry, C., und Muntoni, F. (2004) Abnormalities in a-Dystroglycan Expression
in MDC1C and LGMD2I Muscular Dystrophies. American
Journal of Pathology164: 727-737.
Warth A., Kröger, S., und
Wolburg, H. (2004) Loss of agrin immunoreactivity from
brain capillary basal laminae correlates with the
redistribution of aquaporin-4 in human glioblastoma
multiforme. Acta Neuropathologica 207:
311-318.
Herzog, C., Has, C.,
Franzke, C.-W., Echtermeyer, F.G., Kröger, S., Gustafsson,
E., Fässler, und R., Bruckner-Tuderman, L. (2004)
Dystroglycan in skin and cutaneous cells: b-subunit is shed from the cell
surface. Journal of Investigative Dermatology 122:
1372-1380.
2003
Esapa, C.T.,
Bentham, G.R.B., Schröder, J.E., Kröger, S., und Blake,
D.J. (2003) The effects of post-translational processing
on dystroglycan synthesis and trafficking. FEBS
Letters, 555: 209-216.
2002
Annies, M.,
und Kröger, S. (2002) Isoform pattern and AChR aggregation
activity of agrin expressed by embryonic chick retinal
ganglion neurons. Molecular and Cellular Neuroscience20: 525-535.
Esapa, C. T.,
Benson M. A., Schröder, J. E., Martin-Rendon, E.,
Brockington, M., Brown, S.C., Muntoni, F., Kröger, S., und
Blake, D.J. (2002) Functional requirements for
fukutin-related protein in the Golgi apparatus. Human
Molecular Genetics 11: 3319-3331.
Kröger, S., und Schröder,
J. E. (2002) Agrin in the CNS: New roles for a synapse
organizer. News in Physiological Science17:
207-212.
Rascher, G., Fischmann,
A., Kröger, S., Duffner, F., Grote, E. H., und Wolburg, H.
(2002) Extracellular matrix and the blood-brain barrier in
glioblastoma multiforme: spatial segregation of tenascin
and agrin. Acta Neuropathologica, 104:
85-91.
Blank,
M., Blake, D.J. und Kröger, S. (2002) Molecular
heterogeneity of dystrophin-like complexes in the
developing and adult retina. Neuroscience, 111:
259-273.
Kröger, S.
(2002) Agrin: ein Hauptregulator der Synapsenbildung. BIOforum12: 49-51
2001
Kröger, S. (2001)
Extracellular signals regulating nervous system
development. In: The Neurosciences at the Turn of the
Century. Seite 669-672; Ed. N. Elsner und G. W.
Kreutzberg; Thieme Verlag Stuttgart
Neumann F.R., Bittcher,
G., Annies, M. Schumacher, B. Kröger, S., und Ruegg, M.A.
(2001) An alternative amino-terminus expressed in the
central nervous system converts agrin to a type II
transmembrane protein. Molecular and Cellular
Neuroscience17: 208-225.
Yard, B. A.,
Kahlert, S., Engelleiter, R., Resch, S., Waldherr, R.,
Groffen, A. J., van den Heuvel, L. P. W. J., van der Born,
J., Berden, J. H. M., Kröger, S., Hafner, M., und van der
Woude, F. J. (2001). Decreased glomerular expression of
agrin in diabetic nephropathy and podocytes, cultured in
high glucose medium. Experimental Nephrology9:
214-222.
Schröder,
J.E., Tegeler, M., und Kröger, S. (2001) Die molekulare
Grundlage von Muskeldystrophien. BioForum11:
2-4.
2000
Hering, H., Koulen, P.,
und Kröger, S. (2000) Distribution and subcellular
concentration of b1 integrin
in radial cells of the developing and adult avian retina.
Journal of Comparative Neurology424:
153-164.
Blake, D.J.,
und Kröger, S. (2000) The neurobiology of Duchenne
Muscular Dystrophy: learning lessons from muscle? Trends
in Neurosciences23: 92-99.
Herrmann, R., Straub V.,
Blank, M., Kutzick, C., Franke, N., Neuen Jacob, E.,
Lenard, H.-G., Kröger, S., und Voit, T. (2000)
Dissociation of the dystroglycan-complex in
caveolin-3-deficient Limb Girdle Muscular Dystrophy. Human
Molecular Genetics9: 2335-2340.
1999
Hering, H. und Kröger, S.
(1999) Synapse formation and agrin expression in
stratospheroid cultures from embryonic chick retina. Developmental
Biology214: 412-428.
Koulen, P., Honig, L.S.,
Fletcher, E.L. und Kröger, S. (1999) Expression,
distribution, and ultrastructural localization of the
synapse-organizing molecule agrin in the mature avian
retina. European Journal of Neuroscience11:
4188-4196.
Blank, M., Koulen, P.,
Blake, D., und Kröger, S. (1999) Dystrophin and
beta-dystroglycan in photoreceptor terminals from normal
and mdx3Cv mouse retinae. European
Journal of Neuroscience11: 2121-2133.
1998
Koulen, P., Blank, M., und
Kröger, S. (1998) Differential distribution of
b-dystroglycan in rabbit and rat retina. Journal of
Neuroscience Research51: 735-747.
1997
Kröger, S. (1997)
Differential distribution of agrin isoforms in the
developing and adult avian retina. Molecular and
Cellular Neuroscience10: 149-161.
Blank, M.,
Koulen, P., und Kröger, S. (1997) Subcellular
concentration of b-dystroglycan
in photoreceptor terminals and Müller glial cells of the
chick retina. Journal of Comparative Neurology389:
668-678.
Galarraga, E., und Kröger,
S. (1997) Connections between neuroscientists from Europe
and Latin America reinforced. Trends in Neurosciences20: 549-551.
Sorokin, L.
M., Pausch, F., Frieser, M., Kröger, S., Ohage, E., und
Deutzmann, R. (1997) Developmental regulation of the
laminin a5 chain suggests a
role in epithelial and endothelial cell maturation. Developmental
Biology189: 285-300.
Kröger, S. (1997)
Molecular determinants involved in nervous system
development. In: From Membrane to Mind. Seite
430-433; N. Elsner und H. Wässle; Thieme Verlag,
Stuttgart.
Reiss, Y., Layer, P. G.,
und Kröger, S. (1997) Butyrylcholinesterase-positive cells
of the developing chicken retina that are noncholinergic
and GABA positive. Developmental Brain Research100:
62-72.
Koulen, P., Brandtstätter,
J. H., Kröger, S., Enz, R., Bormann, J., und Wässle, H.
(1997) Immunocytochemical localization of the GABAC
receptor r-subunits in the
cat, goldfish and chicken retina. Journal of
Comparative Neurology380: 520-532.
1996
Mann, S., und Kröger, S.
(1996) Agrin is synthesized by retinal cells and
colocalizes with gephyrin. Molecular and Cellular
Neuroscience8: 1-13.
Hering, H.,
und Kröger, S. (1996) Formation of synaptic
specializations in the inner plexiform layer of the
developing chick retina. Journal of Comparative
Neurology375: 393-405.
Reiss, Y., Kröger, S.,
Grassi, J., Tsim, K.W.K., Willbold, E., und Layer, P.G.
(1996) Extracellular and asymmetric forms of
acetylcholinesterase are expressed on cholinergic and
non-cholinergic terminal neuropil of the developing chick
retina. Cell and Tissue Research286:
13-22.
Jones, G., Herczeg, A.,
Ruegg, M.A., Lichtsteiner, M., Kröger, S., und Brenner,
H.R. (1996) Substrate-bound agrin induces expression of
acetylcholine receptor e-subunit gene in cultured
mammalian muscle cells. Proceedings of the National
Academy of Science (USA)93: 5985-5990.
Kröger, S., und Mann, S.
(1996) Biochemical and functional characterization of
basal lamina-bound agrin in the central nervous system. European
Journal of Neuroscience8: 500-509.
Kirsch, J.,
und Kröger, S. (1996) Postsynaptic anchoring of receptors:
A cellular approach to neuronal and muscular sensitivity.
The Neuroscientist2: 100-108.
Kröger, S.,
Horton, S.E., und Honig, L.S. (1996) The developing avian
retina expresses agrin isoforms during development. Journal
of Neurobiology29: 165-182.
1995
Tsen, G. Halfter, W.
Kröger, S., und Cole, G.J. (1995) Agrin is a heparan
sulfate proteoglycan. Journal of Biological Chemistry270: 3392-3399.
1992
McMahan, U.J., Horton,
S.E., Werle, M.J., Honig, L.S., Kröger, S., Ruegg, M.A.,
und Escher, G. (1992) Agrin isoforms and their role in
synaptogenesis. Current Oppinion in Cell Biology4:
869-874.
Ruegg, M.A., Tsim, K.W.K.,
Horton, S.E., Kröger, S., und McMahan, U.J. (1992) The
agrin gene codes for a family of basal lamina proteins
that differ in function and distribution. Neuron8:
691-699.
Tsim, K.W.K.,
Ruegg, M.A., Escher, G., Kröger, S., und McMahan, U.J.
(1992). cDNA that encodes active agrin. Neuron8:
677-689.
1991
Kröger, S.,
und Walter, J. (1991). Molecular mechanisms separating two
axonal pathways during development of the avian optic
tectum. Neuron6: 291-303.
1990
Kröger, S., und Schwarz,
U. (1990). The avian tectobulbar tract: Development,
explant culture, and effects of antibodies on the pattern
of neurite outgrowth. Journal of Neuroscience10:
3118-3134.
Kröger, S., und
Niehörster, L. (1990). Isolation, characterization and
substrate properties of the external limiting membrane
from the avian embryonic optic tectum. Journal of
Neuroscience Research27: 169-183.
1987
Halfter, W., Reckhaus, W.,
und Kröger, S. (1987). Nondirected axonal growth on basal
lamina from avian embryonic retina. Journal of
Neuroscience7: 3712-3722.
